Ben Stiller will star in A Night at the Museum for 20th Century Fox, reports Variety.
Studio is prepping the family laffer as its major entrant for next year's holiday season.
Stiller will play a night security guard at the Museum of Natural History who unwittingly unleashes a curse that brings to life the bugs and animals on display.
Helming will be Shawn Levy, who directed Fox's "Cheaper by the Dozen." That pic turned into a $139 million hit for Fox after its Christmas 2003 release.